Lyu, Qiong https://orcid.org/0000-0003-3298-7674
Liu, Huiying
Shen, Weitao https://orcid.org/0000-0002-9947-418X
Lin, Zhihong
Zhang, Yueming
Ying, Haoxuan
Long, Qianshan
Cao, Xiang https://orcid.org/0009-0008-8488-9535
Zhang, Jian https://orcid.org/0000-0001-7217-0111
Shi, Jian https://orcid.org/0000-0001-8028-5621
Qiu, Zhengang
Funding for this research was provided by:
National Natural Science Foundation of China (82260546)
National Natural Science Foundation of China (82473364)
Article History
Received: 29 May 2025
Revised: 4 March 2026
Accepted: 9 April 2026
First Online: 29 April 2026
Competing interests
: The authors declare that they have no competing interests. The illustration was generated using Biorender software.
: Ethics approval for this study was obtained from the Ethics Committee of Zhujiang Hospital of Southern Medical University (2024-KY-129-01). Informed consent was obtained from all participants for the collection and use of human tissues. Animal experiments were approved by the Animal Care and Use Committee of Southern Medical University (LAEC-2022-186FS; LAEC-2024-258) and conducted in accordance with the guidelines for the care and use of laboratory animals. All studies and methods were performed in accordance with the relevant guidelines and regulations.
: All the authors have consented to the publication of this manuscript.