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Authors
Nie, Haihang
Yu, Yali
Zhou, Jingkai
Ning, Yumei
Leng, ChunXiao
Qiu, Peishan
Hong, Yuntian
Xu, Fei
Zhao, Qiu https://orcid.org/0000-0002-3230-6077
Wang, Haizhou https://orcid.org/0000-0002-5622-966X
Wang, Fan https://orcid.org/0009-0009-8432-9228
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Funding
Funding for this research was provided by:
National Natural Science Foundation of China (82403279)
National Natural Science Foundation of China (82303181)
National Natural Science Foundation of China (82303248)
the Science and Technology Innovation Cultivation Fund of Zhongnan Hospital of Wuhan University
the Science and Technology Innovation Cultivation Fund of Zhongnan Hospital of Wuhan University
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Article History
Received: 21 September 2025
Revised: 1 April 2026
Accepted: 28 April 2026
First Online: 11 May 2026
Competing interests
: The authors declare no competing interests.
: The study was approved by the Research Ethics Committee of Zhongnan Hospital of Wuhan University, and written informed consent was obtained from all participants in accordance with the Declaration of Helsinki (grant no. 2025001 K). All the methods were carried out in accordance with the relevant guidelines under the ethical approval and consent to participate section. Data collection, analysis, and reporting were conducted following the REMARK guidelines for tumor marker prognostic studies. The study protocol, including animal experiments, was approved by the Institutional Animal Care and Use Committee of Wuhan University (WP20240225).
