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Targeted reduction of the EGFR protein, but not inhibition of its kinase activity, induces mitophagy and death of cancer cells through activation of mTORC2 and Akt

Crossref DOI link: https://doi.org/10.1038/s41389-017-0021-7

Published Online: 2018-01-23

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Katreddy, Rajasekhara Reddy

Bollu, Lakshmi Reddy

Su, Fei

Xian, Na

Srivastava, Shivangi

Thomas, Rintu

Dai, Yubing

Wu, Bing

Xu, Yunlu

Rea, Michael A.

Briggs, James M.

Zhang, Qingyuan

Lu, Xiongbin

Huang, Gangxiong

Weihua, Zhang
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Text and Data Mining valid from 2018-01-23

Version of Record valid from 2018-01-23
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Article History

Received: 16 May 2017

Accepted: 8 November 2017

First Online: 23 January 2018

Conflict of interest

: M.A.R., J.M.B., and Z.W. are co-founders of Metabocentric Biotechnologies Inc. The remaining authors declare that they have no conflict of interest.

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