Zhang, Chen-li https://orcid.org/0009-0007-4071-9553
Zhao, Chan-yuan https://orcid.org/0000-0001-9198-8488
Dong, Jia-ming https://orcid.org/0009-0001-3623-0639
Du, Cun-pu https://orcid.org/0009-0004-3496-8471
Wang, Bin-sheng https://orcid.org/0000-0002-1206-5843
Wang, Chen-yu https://orcid.org/0000-0002-1292-8880
Liu, Wei https://orcid.org/0009-0002-4090-7136
Wang, Yu-ping https://orcid.org/0000-0003-0087-4771
Zhang, Xiao-yu
Zhou, Quan https://orcid.org/0009-0001-8505-2779
Cai, Wei https://orcid.org/0000-0002-2703-4468
Dang, Yun https://orcid.org/0000-0003-0873-4490
Shang, Li-na https://orcid.org/0009-0006-1553-5069
Yang, Ai-jun https://orcid.org/0009-0004-7134-3024
Wang, Min https://orcid.org/0000-0002-8905-6857
Funding for this research was provided by:
National Natural Science Foundation of China (81672399)
National Natural Science Foundation of China (81871919)
Article History
Received: 29 November 2024
Revised: 24 May 2025
Accepted: 4 June 2025
First Online: 20 June 2025
Competing interests
: The authors declare no competing interests.
: All experimental procedures involving human participants were reviewed and approved by the Ethics Committee of the Basic Medical College, Lanzhou University (Approval No. jcyxy20200324), and all animal experiments were approved by the same institution’s Animal Ethics Committee (Approval No. Lzujcyxy20240102). All methods were performed in strict accordance with the relevant national and international guidelines and regulations, including the Declaration of Helsinki for human research and the ARRIVE guidelines for animal studies. Written informed consent was obtained from all human participants prior to their inclusion in the study. All animal procedures were conducted in compliance with institutional animal welfare standards and the Guide for the Care and Use of Laboratory Animals.