Chen, Ziyi https://orcid.org/0009-0003-5679-214X
Duan, Runjie
Chen, Zeqing
Tang, Xinpei
Yang, Wenjin
Yin, Hongjun
Chen, Yijing
Cao, Yiqi
Guo, Hongqian https://orcid.org/0000-0002-3121-5157
Ding, Meng
Ji, Changwei https://orcid.org/0009-0002-4369-6717
Article History
Received: 25 February 2025
Revised: 28 August 2025
Accepted: 11 September 2025
First Online: 7 November 2025
Competing interests
: The authors declare no competing interests.
: All methods conducted in this study were performed in accordance with the Ethics Committee of Nanjing Drum Tower Hospital. For experiments involving human participants, all participants provided explicit and informed consent prior to sample collection and analysis. All patients had been informed of the purpose of the study and agreed to participate. For animals experiments, all procedures were carried out in compliance with the ARRIVE guidelines and relevant national regulations on animals welfare. The animal study protocol was approved by the Animal Ethics Committee of Nanjing Drum Tower Hospital.