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Authors
Dommer, Adam P.
Kyne, Robert
Wang, Jianxin https://orcid.org/0000-0002-0998-4996
O’Connor, Thomas N.
Koren, Amnon
Knudsen, Erik S. https://orcid.org/0000-0002-5130-5969
Witkiewicz, Agnieszka K. https://orcid.org/0000-0003-4538-1145
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Funding
Funding for this research was provided by:
Roswell Park Alliance Foundation, Roswell Park Cancer Institute
U.S. Department of Health & Human Services | NIH | National Cancer Institute (CA247362)
U.S. Department of Health & Human Services | NIH | National Cancer Institute (CA267467)
U.S. Department of Health & Human Services | NIH | National Cancer Institute (P30CA016056)
U.S. Department of Health & Human Services | NIH | National Cancer Institute (CA247362)
U.S. Department of Health & Human Services | NIH | National Cancer Institute (CA267467)
U.S. Department of Health & Human Services | NIH | National Cancer Institute (P30CA016056)
U.S. Department of Health & Human Services | NIH | National Institute of General Medical Sciences (R35GM148071)
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Article History
Received: 7 October 2025
Revised: 24 February 2026
Accepted: 24 March 2026
First Online: 24 April 2026
Competing interests
: Dr. Knudsen has sponsored research funded by Blueprint Medicines and Bristol Myers Squibb and is a member of the Cancer Cell Cycle-LLC consulting enterprise. Dr. Witkiewicz has sponsored research funded by Blueprint Medicines and Bristol Myers Squibb. All other authors declare no potential conflicts of interest.
: All methods relating to animal care, treatment, and sacrifice were approved under protocol number 1384 M by the Institutional Animal Care and Use Committee (IACUC) at Roswell Park in accordance with the NIH Guide for the Care and Use of Laboratory Animals.
