Cavolo, Alice
Gastmans, Chris
Crombag, Neeltje
Article History
Received: 20 June 2024
Revised: 1 October 2024
Accepted: 3 November 2024
First Online: 5 December 2024
Competing interests
: The authors have no financial interest to report. One author, CC was involved in some discussions regarding the ethical aspects of the TOTAL trial and authored four articles included in this review.