Xu, Chendong https://orcid.org/0009-0007-8514-4925
Odamaki, Toshitaka
Hiraku, Akari
Nakata, Setsuko
Arai, Satoshi
Iwabuchi, Noriyuki
Tanaka, Miyuki
Tsuno, Takahisa
Nakamura, Masahiko
Article History
Received: 19 February 2025
Revised: 15 May 2025
Accepted: 21 June 2025
First Online: 18 July 2025
Competing interests
: Chendong Xu, Toshitaka Odamaki, Akari Hiraku, Satoshi Arai, Noriyuki Iwabuchi, and Miyuki Tanaka are employed by Morinaga Milk Industry Co., Ltd. The other authors have no potential conflicts of interest relevant to this article to disclose.
: All participants provided their consent to participate in this study. The study was approved by the Research Ethics Committee of Matsumoto City Hospital on September 27, 2019. This clinical trial was registered at under accession number UMIN000038351.