Eldred-Evans, David http://orcid.org/0000-0002-6861-8160
Winkler, Mathias http://orcid.org/0000-0002-2553-5816
Klimowska-Nassar, Natalia
Burak, Paula
Connor, Martin J. http://orcid.org/0000-0003-4033-7508
Fiorentino, Francesca
Day, Emily
Price, Derek
Gammon, Martin
Tam, Henry
Sokhi, Heminder
Padhani, Anwar R. http://orcid.org/0000-0002-5830-5777
Ahmed, Hashim U. http://orcid.org/0000-0003-1674-6723
Article History
Received: 29 May 2022
Revised: 26 February 2023
Accepted: 14 March 2023
First Online: 31 March 2023
COMPETING interests
: DE-E reports grants from the BMA Foundation for Medical Research, a Urology Foundation Research Scholarship and a Royal College of Surgeons of England Research Fellowship during the conduct of the study; grants from Imperial Health Charity outside the submitted work. MW reports personal fees and non-financial support from Zicom Biobot outside the submitted work; HUA reports grants from Wellcome Trust during the conduct of the study; grants from Medical Research Council grants from Cancer Research UK (CRUK), Prostate Cancer UK and National Institute for Health Research (NIHR). Grants and personal fees from Sonacare Inc, Sophiris Biocorp and Boston Scientific outside the submitted work. The remaining authors declare no competing interests.
: This study was approved by the UK National Research Ethics Committee (8/LO/1338) and conducted in accordance with Good Clinical Practice guidelines and the Declaration of Helsinki. All participants provided written informed consent. The study was managed by the Imperial Clinical Trials Unit, overseen by an Independent Trial Steering Committee.