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Authors
Zhang, Pei-Pei
Li, Man-Sheng https://orcid.org/0000-0002-0778-0965
Zhou, Jia
Zhu, Chu-Hong
Tang, Rui
He, Zhi-Cheng
Yao, Xiao-Hong https://orcid.org/0000-0002-4689-9141
Ping, Yi-Fang https://orcid.org/0000-0002-0699-8401
Xiang, Dong-Fang
Tan, Le-Yong
Wang, Yu-Jie
Wang, Shuai
Li, Si-Si
Ma, Jie https://orcid.org/0000-0002-8934-922X
Zhu, Yun-Ping
Bian, Xiu-Wu https://orcid.org/0000-0003-4383-0197
Leng, Ling https://orcid.org/0000-0002-6519-012X
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Article History
Received: 14 July 2025
Revised: 25 November 2025
Accepted: 22 December 2025
First Online: 4 February 2026
Competing interests
: The authors declare that they have no competing interests. Xiuwu Bian is the editorial board member of Signal Transduction and Targeted Therapy, but he has not been involved in the process of manuscript handling.
: All samples and clinical data were obtained with informed consent from their guardians. The study was performed in accordance with the cohort hospital ethics committee regulations, the National Health Commission of China, and the Helsinki Declaration. This study was approved by the Research Ethics Committee of Southwest Hospital of Third Military Medical University (KY2020298).
: The brain samples used in this study were obtained from deceased donors, and all personal identifying information (such as names or specific locations) was removed. The study was conducted in accordance with ethical guidelines and institutional approvals, and the use of these samples for publication does not require individual consent.
