Guo, Xiaofan
Liu, Yuxiao
Li, Tianchen
An, Xiaopeng
Song, Yuning
Xu, Peijun
Huang, Jing
Zou, Yiping
Xu, Bohang
Xie, Yongjie
Li, Zekun
Meng, Chenyang
Zhao, Tiansuo
Wang, Xiuchao https://orcid.org/0000-0002-3205-8544
Wang, Hongwei
Gao, Chuntao
Zhou, Xuan https://orcid.org/0000-0002-1967-3593
Yu, Jun https://orcid.org/0000-0003-3435-6550
Gao, Song
Hao, Jihui
Funding for this research was provided by:
National Natural Science Foundation of China (82430057, 82030092)
National Natural Science Foundation of China (82473338)
Tianjin Key Medical Discipline(Specialty)Construction Projec(TJYXZDXK-009A).
Natural Science Foundation of Tianjin City (24JCYBJC00580)
Article History
Received: 16 April 2025
Revised: 24 January 2026
Accepted: 10 February 2026
First Online: 28 April 2026
Competing interests
: The authors declare no competing interests.
: All human sample manipulation involved in this study was in accordance with the Declaration of Helsinki and related ethical norms, and was approved by the Ethics Committee of Tianjin Medical University Cancer Hospital (approval number: EK20240448). All participants signed informed consent forms. All animal procedures involved in this study followed the international guidelines for the care and use of laboratory animals and were approved by the Laboratory Animal Ethics Committee of Tianjin Medical University Cancer Institute and Hospital (approval number: 2021045).