Park, Jeongwoo
Kim, Taeeung
Shim, Wan Seob
Hong, Sung Eun https://orcid.org/0000-0003-3437-8936
Park, Miso
Oh, Seungseok
Koo, Bo Kyung
Lee, Dong Hyeon
Joo, Sae Kyung
Yoo, Taekyeong
Lee, Young Joo
Lim, Sung-Chul
Seo, Seung-Yong
Kim, Kyu Min
Nieto, Natalia
Choi, Murim https://orcid.org/0000-0002-9195-1455
Kim, Won https://orcid.org/0000-0002-2926-1007
Kang, Keon Wook
Funding for this research was provided by:
National Research Foundation of Korea (RS-2022-NR067269)
National Research Foundation of Korea (2021M3A9E4021818)
National Research Foundation of Korea (RS-2022-NR067269)
National Research Foundation of Korea (2021M3A9E4021818)
Article History
Received: 5 January 2024
Revised: 15 February 2026
Accepted: 8 March 2026
First Online: 6 May 2026
Competing interests
: The authors declare no competing interests.
: All animals received humane care throughout the study. All animal protocols were approved by the IACUC at Seoul National University (SNU-220114-1-2, SNU-201102-3-3, and SNU-200720-3-2) and conducted in accordance with the criteria outlined in the Guide for the Care and Use of Laboratory Animals . For human liver samples, the study was conducted in accordance with the provisions of the Declaration of Helsinki for the participation of human subjects in research and was approved by the Institutional Review Board of Boramae Medical Center (IRB No. 16-2013-45). Written informed consent was obtained from each subject in the study cohort.