Gil-Agudo, Ángel https://orcid.org/0000-0001-5082-4225
Gutiérrez Henares, Francisco https://orcid.org/0000-0003-3550-5394
Biscotto, Sauro
Rodriguez Sotillo, Antonio
Ferreiro Velasco, Mª Elena
Méndez Ferrer, Bosco
Benito Penalva, Jesús https://orcid.org/0000-0003-1232-1808
Vidal Samsó, Joan
Borau Duran, Albert
del Popolo, Giulio
Petrozzino, Salvatore
Losavio, Ernesto
Onesta, Maria Giuseppa
Spinelli, Michele https://orcid.org/0000-0002-6245-0205
Article History
Received: 28 June 2024
Revised: 26 May 2025
Accepted: 15 July 2025
First Online: 17 September 2025
Competing interests
: The authors declare no competing interests.
: The study was approved by the Ethics Committee. All the procedures were in accordance with the ethical principles of the Declaration of Helsinki, following good clinical practice (GCP) and ICH guidelines.
: Written informed content was obtained from all subjects before study-related procedures.