Shi, Zhiyang https://orcid.org/0000-0002-4454-8495
Sweet, Shane N. https://orcid.org/0000-0002-6172-3769
Routhier, François https://orcid.org/0000-0002-5458-6233
Borisoff, Jaimie
Arbour-Nicitopoulos, Kelly P.
Best, Krista L. https://orcid.org/0000-0001-7205-7725
Funding for this research was provided by:
Canada Research Chairs (950-232143, 950-230997)
Article History
Received: 16 December 2024
Revised: 15 October 2025
Accepted: 22 October 2025
First Online: 6 November 2025
Competing interests
: The authors declare no competing interests.
: The study procedures were registered (NCT02826707) and approved by the Research Ethics Boards of each local research site (MP-13-2018-415, 2018-18). All participants provided informed consent. All methods were performed in accordance with the relevant guidelines and regulations.