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Article History

Received: 22 March 2022

Revised: 10 May 2024

Accepted: 15 May 2024

First Online: 29 May 2024

Ethical approval and consent

: All data used in this study was obtained from participants having given written informed consent. Specific ethical approval statements given in the original publications are below. <i>“The UK Biobank received ethical approval from the Research Ethics Committee (REC reference for the UK Biobank is 11/NW/0382). All participants gave full informed written consent”</i> [], <i>“All [CHARGE] cohort participants gave written informed consent, including consent to participate in genetic studies. All studies received approval from local ethical oversight committees”</i> [], <i>“The BiDirect cohort and the Münster cohort were approved by the ethics committee of the University of Münster and the Westphalian Chamber of Physicians in Münster, North-Rhine-Westphalia, Germany, and written informed consent was obtained from all participants.” Generation Scotland received core support from the Chief Scientist Office of the Scottish Government Health Directorates [CZD/16/6] and the Scottish Funding Council [HR03006]. Genotyping of the GS:SFHS samples was carried out by the Genetics Core Laboratory at the Wellcome Trust Clinical Research Facility, Edinburgh, Scotland and was funded by the Medical Research Council UK and the Wellcome Trust (Wellcome Trust Strategic Award “STratifying Resilience and Depression Longitudinally” (STRADL) Reference 104036/Z/14/Z). Ethics approval for Generation Scotland was given by the NHS Tayside Committee on Research Ethics (reference 15/ES/0040), and all participants provided written informed consent for the use of their data. The study protocol used by 23andMe was approved by an external AAHRPP-accredited institutional review board. Details of the manuscripts containing approvals for the 35 PGC cohorts are listed in</i> Supplementary Tables <i>and</i><i>of Wray</i> et al.” [].

: The authors declare no competing interests.