Simmonds, Emily https://orcid.org/0000-0001-5691-597X
Leonenko, Ganna
Yaman, Umran
Bellou, Eftychia
Myers, Amanda
Morgan, Kevin
Brookes, Keeley https://orcid.org/0000-0003-2427-2513
Hardy, John
Salih, Dervis
Escott-Price, Valentina https://orcid.org/0000-0003-1784-5483
Funding for this research was provided by:
RCUK | Medical Research Council (UKDRI-3003)
Article History
Received: 26 October 2023
Revised: 20 August 2024
Accepted: 22 August 2024
First Online: 4 September 2024
Competing interests
: The authors declare no competing interests.
: All methods were performed in accordance with the relevant guidelines and regulations. The KRONOS/Tgen study is declared not human-subjects research and is IRB exempt under regulation 45 CFR 46. The Brains for Dementia Research (BDR) datahas ethics approval from London – City and East NRES committee 08/H0704/128 + 5 and has deemed all approved requests for tissue to have been approved by the committee. For ROSMAP the parent studies and sub-studies were all approved by an Institutional Review Board of Rush University Medical Center. All participants signed an informed consent and Anatomical Gift Act; in addition, they signed a repository consent allowing their data to be shared. Data documentation and sharing documents can be obtained at .