Bai, Zhixin
Li, Peilong https://orcid.org/0009-0002-7411-3676
Gao, Xu
Zu, Gaoyu
Jiang, Andrew https://orcid.org/0000-0002-7267-013X
Wu, Keting
Mechawar, Naguib https://orcid.org/0000-0003-4960-756X
Turecki, Gustavo https://orcid.org/0000-0003-4075-2736
Lehnert, Klaus
Snell, Russell G.
Zhou, Jin
Hu, Jia
Yan, Bingbing
Chen, Liang
Li, Wensheng
Chen, You https://orcid.org/0000-0003-4776-6380
Liu, Shuai https://orcid.org/0000-0001-5849-489X
Zhu, Ying https://orcid.org/0000-0002-6594-3734
You, Linya https://orcid.org/0000-0002-2569-0269
Funding for this research was provided by:
Ministry of Science and Technology of the People's Republic of China (2021ZD0201100 Task 4 2021ZD0201104, 2021ZD0201100 Task 4 2021ZD0201104, 2023YFF1204802, 2021ZD0200100)
Natural Science Foundation of Shanghai (21ZR1419700)
National Natural Science Foundation of China (82071259)
Article History
Received: 28 February 2024
Revised: 2 December 2024
Accepted: 10 December 2024
First Online: 18 December 2024
Competing interests
: The authors declare no competing interests.
: The study was conducted in compliance with the National Institutes of Health Guide for the Care and Use of Laboratory Animals. All animal procedures were approved by the Animal Ethics Committee of School of Basic Medical Sciences at Fudan University. Human brain samples were obtained from Fudan branch of National Health and Disease Human Brain Tissue Resource Center, the Body Donation Station in Fudan University (Shanghai Red Cross Society). Human postmortem brain tissue from two control and two BD donors of Asian ancestry (Table ) was obtained under ethic approval 2018C001 by the Ethics Committee of School of Basic Medical Sciences at Fudan University. Human caudate paraffin sections of five control and five BD donors of Caucasian ancestry were kindly provided by Douglas-Bell Canada Brain Bank (Table ).