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Linking altered neuronal and synaptic properties to nicotinic receptor Alpha5 subunit gene dysfunction: a translational investigation in rat mPFC and human cortical layer 6

Crossref DOI link: https://doi.org/10.1038/s41398-025-03230-9

Published Online: 2025-01-17

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Yang, Danqing https://orcid.org/0000-0001-7893-9446
Qi, Guanxiao https://orcid.org/0000-0001-7054-1249
Delev, Daniel

Maskos, Uwe https://orcid.org/0000-0002-2029-1437
Feldmeyer, Dirk https://orcid.org/0000-0002-1716-8972
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Text and Data Mining valid from 2025-01-17

Version of Record valid from 2025-01-17
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Article History

Received: 6 May 2024

Revised: 9 December 2024

Accepted: 10 January 2025

First Online: 17 January 2025

Competing interests

: The authors declare no competing interests.

: All experimental procedures involving animals were performed in accordance with the guidelines of the Federation of European Laboratory Animal Science Associations (FELASA), the EU Directive 2010/63/EU, and the German Animal Welfare Law. For research involving human tissues, the study was reviewed and approved by the ethics committee of RWTH Aachen University Hospital (EK067/20).

: Written informed consent was obtained from all patients for the use of spare neocortical tissue acquired during surgical procedures.

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