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Antidepressant effects of ershiwei roudoukou pills and its active ingredient Macelignan: Multiple mechanisms involving oxidative stress, neuroinflammation and synaptic plasticity

Crossref DOI link: https://doi.org/10.1038/s41398-025-03378-4

Published Online: 2025-05-09

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Wang, Yan-Li

Chen, Lei

Zhong, Xiao-Lin

Liu, Qing-Shan

Li, Wen-Qiang https://orcid.org/0000-0002-0833-246X
Cheng, Yong https://orcid.org/0000-0002-7529-4408
Du, Yang https://orcid.org/0000-0002-9013-3178
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Text and Data Mining valid from 2025-05-09

Version of Record valid from 2025-05-09
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Article History

Received: 19 November 2024

Revised: 25 March 2025

Accepted: 7 April 2025

First Online: 9 May 2025

Competing interests

: The authors declare no competing interests.

: All animal experiments in this study were conducted in accordance with the National Institutes of Health Laboratory Animal Care and Use Guidelines (NIH Publication No. 80–23) and approved by the Animal Care and Use Committee of Minzu University of China.

: During the preparation of this work the author(s) used Chatgpt in order to improve language and readability, with caution. After using this tool, the author(s) reviewed and edited the content as needed and take(s) full responsibility for the content of the publication.

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