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Authors
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Funding
Funding for this research was provided by:
National Natural Science Foundation of China (82171508, 82071507)
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Article History
Received: 5 March 2025
Revised: 12 August 2025
Accepted: 3 September 2025
First Online: 10 October 2025
Competing interests
: The authors declare no competing interests.
: The research protocol was reviewed and approved by the Medical Research Ethics Committee of the Second Xiangya Hospital of Central South University and the Second Affiliated Hospital of Xinxiang Medical University. All participants provided written informed consent before enrollment. All methods were carried out in accordance with relevant guidelines and regulations.
