Miranda-Barrientos, Jorge https://orcid.org/0000-0003-1161-5695
Adiraju, Suhaas https://orcid.org/0000-0003-0062-9493
Rehg, Jason J. https://orcid.org/0009-0009-7947-4746
Totty, Michael S. https://orcid.org/0000-0002-9292-8556
Hallock, Henry L. https://orcid.org/0009-0002-4198-7430
Li, Ye https://orcid.org/0009-0008-5747-852X
Carr, Gregory V. https://orcid.org/0000-0002-6091-6729
Martinowich, Keri https://orcid.org/0000-0002-5237-0789
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R56MH126233, R01MH137057, R56MH126233, R01MH137057, R56MH126233, R56MH126233, R01MH137057, R56MH126233, R56MH126233, R01MH137057, R56MH126233, R01MH137057, R01MH137057, R56MH126233)
Article History
Received: 26 July 2024
Revised: 24 September 2025
Accepted: 10 October 2025
First Online: 7 November 2025
Competing interests
: GVC is a scientific advisor for LongTermGevity, Inc. and owns stock options in the company. LongTermGevity, Inc. was not involved in the funding, design, or execution of these studies. No other authors have financial relationships with commercial interests, and the authors declare no competing interests.
: All procedures were approved by the Johns Hopkins University Animal Care and Use Committee and were in accordance with the Guide for the Care and Use of Laboratory Animals (M022L263).