Donegan, Kelly R.
Hossein, Shabnam https://orcid.org/0009-0009-0698-5369
Panny, Benjamin M.
Brown, Vanessa M. https://orcid.org/0000-0003-0968-1095
Lee, Chi Tak
Harty, Siobhan
Lynch, Kevin
Fox, Celine
Hanlon, Anna K.
O’Keane, Veronica
Stephan, Klaas E. https://orcid.org/0000-0002-8594-9092
Gillan, Claire M. https://orcid.org/0000-0001-9065-403X
Price, Rebecca B. https://orcid.org/0000-0002-7590-4325
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Institute of Mental Health (R01 MH113857)
MQ: Transforming Mental Health (MQ16IP13)
Article History
Received: 23 March 2025
Revised: 23 September 2025
Accepted: 21 October 2025
First Online: 27 November 2025
Competing interests
: KRD, SH, KL, CF, AKH, VOK, KES, BMP and CMG have no conflicts of interest to declare. CTL and SiH are current employees of SilverCloud Health. VMB has received consulting fees from Aya Technologies. KES acknowledges core funding by the Rene and Susanne Braginsky Foundation and the ETH Foundation. RBP is the named inventor on a University of Pittsburgh–owned patent filing related to the combination intervention that was used in the parent clinical trial.