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Authors
Cai, Yi
Eguchi, Akifumi
Murayama, Rumi
Ding, Xin
Yue, Yong
Niitsu, Tomihisa
Oda, Yasunori
Futamura, Takashi
Yang, Jian-Jun
Nakamura, Hiroyuki
Hashimoto, Kenji https://orcid.org/0000-0002-8892-0439
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Funding
Funding for this research was provided by:
MEXT | Japan Science and Technology Agency (JPMJSP2109)
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Article History
Received: 17 January 2026
Revised: 29 March 2026
Accepted: 30 April 2026
First Online: 14 May 2026
Competing interests
: Dr. Hashimoto has received research support from Otsuka Pharmaceutical Co., Ltd. (Japan). Dr. Futamura is an employee of Otsuka Pharmaceutical Co., Ltd. (Japan). The other authors declare no competing interests related to this study.
: All animal procedures were performed in accordance with the Guidelines for Animal Experimentation of Chiba University, and the study protocol was approved by the Animal Care and Use Committee of Chiba University (approval no. 6-406 and 7-316), in accordance with the Japanese national guidelines for animal experimentation. Every effort was made to minimize animal suffering and reduce the number of animals used.
