Bryant, Linda https://orcid.org/0009-0008-1249-5975
Alexander, Laith https://orcid.org/0000-0003-1297-6548
Mena, Sergio
Jacob, Yael https://orcid.org/0000-0003-3278-9264
Jubeir, Jenna https://orcid.org/0009-0009-2338-9593
Li, Mu
Neukam, Philipp T. https://orcid.org/0000-0002-9442-0043
Morris, Laurel S. https://orcid.org/0000-0002-5862-6650
Murrough, James W. https://orcid.org/0000-0001-6286-1242
Price, Rebecca https://orcid.org/0000-0002-7590-4325
Koutsouleris, Nikolaos
Mehta, Mitul A. https://orcid.org/0000-0003-1152-5323
Juruena, Mario https://orcid.org/0000-0001-8558-3396
Coutts, Fiona
Lalousis, Paris Alexandros https://orcid.org/0000-0001-9642-3080
Funding for this research was provided by:
RCUK | Engineering and Physical Sciences Research Council (EP/Y035216/1)
Article History
Received: 29 December 2025
Revised: 9 April 2026
Accepted: 30 April 2026
First Online: 12 May 2026
Competing interests
: In the past 24 months, Dr. Murrough has provided consultation services for Autobahn Therapeutics, Inc., Biohaven Pharmaceuticals, Inc., Cliniclabs, Inc., Clexio Biosciences, Ltd., Compass Pathfinder, Plc., Dr Jay, Frontier Pharma, LLC, HMP Collective, Janssen Pharmaceuticals, LivaNova, Plc., Merck & Co., Inc., Otsuka Pharmaceutical, Ltd, WCG Clinical, Inc., and Xenon Pharmaceuticals, Inc. The Icahn School of Medicine (employer of Dr. Murrough) is named on a patent and has entered into a licensing agreement and will receive payments related to the use of ketamine or esketamine for the treatment of depression. The Icahn School of Medicine is also named on a patent related to the use of ketamine for the treatment of PTSD. Dr. Murrough is not named on these patents and will not receive any payments. Prof. Mehta has provided consultation services for Neurocentrx, Curie.bio and Nxera. Prof. Price is the named inventor on a University of Pittsburgh-owned patent filing optioned to TaJa Health, Inc., and has received consulting fees from Lightstone Ventures. Dr. Lalousis has received honoraria for talks presented at educational meetings organized by Boehringer Ingelheim outside the submitted work. All other authors report no potential conflicts of interest.