Lyu, Congmin
Wang, Ziying
Zhao, Ruojin
Zhao, Haiping
Liu, Sheng
Lian, Hong
Wang, Xin https://orcid.org/0009-0009-4849-391X
Funding for this research was provided by:
National Clinical Research Center for Cardiovascular Diseases, Fuwai Hospital, Chinese Academy of Medical Sciences
National Key R&D Program of China
Article History
Received: 26 November 2025
Revised: 28 April 2026
Accepted: 3 June 2026
First Online: 12 June 2026
Competing interests
: The authors declare no competing interests.
: Written informed consent was obtained from all participants prior to enrollment. The study was conducted in accordance with the Declaration of Helsinki and approved by the Institutional Review Board of Fuwai Hospital (Approval No. 2021-1466; September 19, 2022). The study was registered at ClinicalTrials.gov (NCT05628480; Registered 31 October 2023 – Retrospectively registered; ).