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Postmortem brain single-nucleus and bulk gene expression analyses identify shared and distinct abnormalities in bipolar disorder and major depressive disorder

Crossref DOI link: https://doi.org/10.1038/s41398-026-04200-5

Published Online: 2026-06-21

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Gao, Rongwei https://orcid.org/0009-0009-6805-6020
Otsuka, Ikuo https://orcid.org/0000-0002-2831-9158
Shirai, Toshiyuki https://orcid.org/0009-0009-2058-1678
Miyachi, Masao

Minami, Kiriko

Okada, Shohei

Tsukamoto, Ryo

Tanifuji, Takaki

Okazaki, Satoshi

Hishimoto, Akitoyo
Funding

Funding for this research was provided by:

JST Moonshot R&D Program (JPMJMS239F) SENSHIN Medical Research Foundation Smoking Research Foundation

JST SPRING

MEXT | Japan Society for the Promotion of Science (JP25K19058)

MEXT | Japan Society for the Promotion of Science (JP21K07520 JP24K10710)

MEXT | Japan Society for the Promotion of Science (JP21H02852 JP24K02383)

Japan Agency for Medical Research and Development (23dk0307111)

JST Moonshot R&D Program (JPMJMS239F) Smoking Research Foundation
License Information

Text and Data Mining valid from 2026-06-21

Accepted Manuscript valid from 2026-06-21
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Article History

Received: 10 December 2025

Revised: 19 May 2026

Accepted: 12 June 2026

First Online: 21 June 2026

Competing interests

: The authors declare no competing interests.

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