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Comprehensive multi-omics analysis elucidates colchicine-induced toxicity mechanisms and unveils the therapeutic potential of MLN4924 and kinase inhibitors

Crossref DOI link: https://doi.org/10.1038/s41401-024-01422-5

Published Online: 2024-11-20

Published Print: 2025-03

Update policy: https://doi.org/10.1007/springer_crossmark_policy

Authors

Zhai, Lin-hui

Jia, Xing-long

Chen, Yu-lu

Liu, Mu-yin

Zhang, Jing-dan

Ma, Shao-jie

Wang, Xiu-jun

Cheng, Wen-hao

He, Jing-liang

Zhou, Jiao-jiao

Zuo, Ling-yi

Zhang, Mei-qi

Yuan, Qing

Xu, Meng-han

Ji, Jing

Tan, Min-jia

Liu, Bin
License Information

Text and Data Mining valid from 2024-11-20

Version of Record valid from 2024-11-20
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Article History

Received: 28 August 2024

Accepted: 5 November 2024

First Online: 20 November 2024

Competing interests

: The patent application (ZL 2021 1 0280667.1) was filed by Min-jia Tan, Bin Liu, and Lin-hui Zhai for the novel application of MLN4924 in alleviating colchicine poisoning. All the authors in this project declare that they have no competing interests.

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