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Article History

Received: 2 November 2022

Revised: 27 December 2022

Accepted: 10 January 2023

First Online: 25 January 2023

Competing interests

: GP reports participating in advisory boards for Alexion, Argobio, Janssen, and Protego; honoraria from Alexion, Argobio, Janssen, Protego, The Binding Site, Pfizer, Prothena, Sebia, and Siemens; research funding from Gate bioscience and The Binding Site. SS reports research support from Janssen, Prothena, and Sanofi; participating in advisory boards for Janssen, Telix, and Prothena; honoraria from Janssen, Takeda, Pfizer, and Prothena; travel and congress participation grants from Janssen, Prothena, Celgene, Binding Site, and Jazz. PM reports speaker honoraria from Janssen and Pfizer; participating in advisory board for Janssen. AJ reports honoraria from Servier, Amgen, Abbvie, and Pfizer; participating in advisory committees for Janssen; research funding from Sanofi and Janssen. FB reports lecture fees from Janssen, Astra Zeneca, GSK, and Novartis; consultancy for Janssen and Astra Zeneca. MAD reports honoraria from participation in advisory boards from Amgen, Takeda, Beigene, BMS, and Janssen. UH reports travel grants from Janssen, Prothena, and Pfizer; participating in advisory boards for Pfizer, Janssen, and Prothena; honoraria from Janssen, Pfizer, Alnylam, and Akcea; research funding from Janssen and Prothena. WR reports honoraria/advisory board from Janssen, MSD, Amgen, and Sanofi. MTC reports honoraria for lectures/advisory board for Janssen, Amgen, Akcea, and Sanofi. MCC reports honoraria from BMS; consultancy for Janssen-Cilag and Gilead; speaker’s bureau for Medscaoe. RH reports consultancy/advisory relationship with Janssen, Amgen, Celgene, Abbvie, BMS, Novartis, PharmaMar, and Takeda; honoraria from Janssen, Amgen, Celgene, BMS, PharmaMar, and Takeda; research funding from Janssen, Amgen, Celgene, BMS, Novartis, and Takeda. CJ reports scientific advisory for Takeda, BMS, Janssen, GSK, and Amgen; research funding from Takeda. AL reports current employment with Health Data Specialists. GC reports current employment with Health Data Specialists. PS reports research support from Janssen, BMS, Sanofi, and Amgen, all for EMN trials; participating in advisory boards for Janssen, BMS, Sanofi, Amgen, Cargen, and Pfizer. EK reports honoraria/advisory board from Genesis Pharma, Janssen, GSK, and Pfizer; research support from Amgen, Janssen, and Pfizer. AW reports honoraria/advisory board from Janssen, Alexion, Attralus, Celgene/BMS, Takeda, and GSK. All remaining authors have declared no conflicts of interest.