McCurdy, Arleigh http://orcid.org/0000-0002-8809-4368
Reece, Donna http://orcid.org/0000-0002-7201-4642
Louzada, Martha L.
White, Darrell
Parkin, Stephen
Chu, Michael P.
Kotb, Rami
Mian, Hira
Othman, Ibraheem
Su, Jiandong
Khan, Aniba
Gul, Engin http://orcid.org/0000-0002-3922-3215
Trudel, Suzanne
Funding for this research was provided by:
Study was sponsored by the Canadian Myeloma Research Group (CMRG) with support from Glaxo-Smith-Kline
Article History
Received: 22 March 2024
Revised: 24 July 2024
Accepted: 28 August 2024
First Online: 11 September 2024
Competing interests
: The authors declare the following competing interests: AM received honoraria from Celgene, Janssen, Amgen, Takeda, Sanofi, and GSK. DR received research funding and honoraria from, and is on the advisory board of, Janssen, BMS, and Takeda; received research funding from Millennium Pharmaceuticals; and received honoraria from Amgen, Sanofi, and GSK. ML received research support from BMS/Celgene and Janssen; and honoraria from BMS/Celgene, Janssen, Gilead, AbbVie, AstraZeneca, and Takeda. SP received consultancy honoraria from Janssen, BMS, FORUS, and Apotex; study funding from GSK; and funding from BMS. DW received honoraria from Amgen, Antengene, BMS, FORUS Therapeutics, GSK, Janssen, Karyopharm, Pfizer, Sanofi, and Takeda. MC received research support from BMS/Celgene and Janssen; and honoraria from BMS/Celgene, Janssen, Gilead, AbbVie, AstraZeneca, and Takeda. RK received honoraria from Akcea Therapeutics, Amgen, BMS, Janssen, Merck, Sanofi, Celgene, Pfizer, and Takeda; received research funding from Merck and Sanofi; and is a current equity holder in the private company Karyopharm. HM received advisory fees from Janssen, Takeda, Amgen, Pfizer, BMS, FORUS, and Sanofi; received research funding from Janssen; and is supported by the early career award from Hamilton Health Sciences. IO participated in advisory boards for and received honoraria from Amgen, BMS, Celgene, FORUS Therapeutics, Janssen, Pfizer, Sanofi-Genzyme, and Takeda; and received research funding from Janssen. JS, AK, and EG are employees of CMRG. ST received grant support from GSK, Bristol Myers Squibb (BMS), Janssen, Pfizer, Amgen, Roche, and Genentech; consulting fees from BMS, GSK, and Roche; and honoraria from BMS, Janssen, Amgen, Sanofi, and Pfizer.
: The trial was conducted in accordance with the Declaration of Helsinki, International Council Harmonization Good Clinical Practice Guidelines, local regulation governing the conduct of clinical studies and institutional guidelines. Approval to conduct the trial was provided by Ontario Cancer Research Ethics Board (OCREB; IRB00003960); project ID 1598. Informed consent was obtained from all patients.