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Authors
Akiyama, Hiroki https://orcid.org/0000-0003-2627-1055
Nishida, Yuki
Chang, Kyung Hee
Bedoy, Andrea D.
Muftuoglu, Muharrem
Ma, Wencai
Basyal, Mahesh
Hirschi, Zoe https://orcid.org/0000-0002-9424-5417
Honma, Daisuke
Tsutsumi, Shinji
Wang, Jing
Zhang, Weiguo
Huang, Xuelin https://orcid.org/0000-0003-1192-9336
Rampal, Raajit K. https://orcid.org/0000-0002-0355-6368
Oluwole, Olalekan O.
Bixby, Dale Lee
Daver, Naval G. https://orcid.org/0000-0001-7103-373X
Andreeff, Michael https://orcid.org/0000-0002-1144-1958
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Funding
Funding for this research was provided by:
U.S. Department of Health & Human Services | NIH | National Cancer Institute (P30 CA016672, 1 R50 CA243707-01A1)
Daiichi Sankyo Company
Cancer Prevention and Research Institute of Texas (RP121010)
Uehara Memorial Foundation (NA)
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Article History
Received: 20 September 2024
Revised: 24 January 2025
Accepted: 25 March 2025
First Online: 24 April 2025
Competing interests
: DH and ST are employees of Daiichi-Sankyo, Co., Ltd., NGD: Consultancy and Research Funding, Daiichi-Sankyo; OOO: Consultancy and advisory board for: Pfizer, Kite, Gilead, AbbVie, Janssen, TGR therapeutics, ADC, Novartis, Epizyme, Curio science, Nektar, Cargo, Caribou, Autolus, Bioheng, Allogene, BMS. Institution funding: Kite, Pfizer, Daichi Sankyo, Cargo, Caribou, Sana, Century Allogene, Abbvie. MA: Consultancy and Research Funding, Daiichi-Sankyo Inc.; Research Funding, Oxford Biomedical, Eterna Therapeutics Inc., Senti Bio, Sellas, Ellipses Pharma, Kintor Pharmaceutical Ltd., Syndax; Stocks or stock options, Eutropics, SentiBio, Eterna, Chimerix, Oncolyze; Honoraria, Eterna, SentiBio, Syndax, Glycomimetics, Aptose, Ona, Sellas, Boehringer-Ingelheim, Paraza, Roivant.
: DS3201-A-U102 clinical trial and associated preclinical study were conducted in accordance with Good Clinical Practice guidelines and the principles of the Declaration of Helsinki and were approved by the Independent Ethics Committee or Institutional Review Board (2016-1130). Written informed consent was obtained from all patients before study enrollment and sample collection. The animal study was performed following the guidelines approved by the Institutional Animal Care and Use Committees at MD Anderson Cancer Center (00001303-RN02).
