Shen, Hao-Rui
Wu, Jia-Zhu
Yin, Hua
Du, Kai-Xin
Sibusiso, Luthuli
Wu, Yi-Fan
Hua, Wei
Li, Yue
Kong, Yi-Lin
Zhang, Xin-Yu
Gao, Rui
Li, Jian-Yong https://orcid.org/0000-0002-9931-4055
Wang, Li
Liang, Jin-Hua
Funding for this research was provided by:
National Natural Science Foundation of China (82370194)
National Natural Science Foundation of China (82200887)
China Postdoctoral Science Foundation (2022M7114034)
China Postdoctoral Science Foundation (2023M741463)
Article History
Received: 10 June 2025
Revised: 1 December 2025
Accepted: 27 January 2026
First Online: 11 February 2026
Competing interests
: The authors declare no competing interests.
: This study was approved by an institutional review board and ethics committee at Jiangsu Province Hospital in accordance with the Declaration of Helsinki (2022-SR-166). All patients gave written informed consent before enrollment. The study is registered on clinicaltrials.gov (NCT05347641). The study protocol is available online.