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Authors
Xiao, Pingnan https://orcid.org/0009-0006-5425-8623
Zhao, Xin
Wang, Linqin
Liu, Kanfeng
Li, Yixue
Zhang, Mingming
Zhang, Yafei
Liu, Yinuo
Feng, Jingjing
Hong, Ruimin
Fu, Shan
Zhao, Houli
Cui, Jiazhen
Xu, Huijun
Wu, Xiaoyu
Zhang, Yanlei
Wei, Guoqing
Chang, Alex Hongsheng
Zhao, Kui
Huang, He https://orcid.org/0000-0002-2723-1621
Hu, Yongxian https://orcid.org/0000-0001-9564-1852
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Funding
Funding for this research was provided by:
National Natural Science Foundation of China (82425002)
National Natural Science Foundation of China (81900104)
National Natural Science Foundation of China (82130003)
The Key Research and Development Program of Zhejiang Province
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Article History
Received: 5 August 2025
Revised: 10 October 2025
Accepted: 11 November 2025
First Online: 13 December 2025
Competing interests
: Competing Interests: Authors Yanlei Z and AHC are employed by Shanghai YaKe Biotechnology. However, the other authors declare no competing interests.
: The study protocol received approval from the Institutional Review Board of the First Affiliated Hospital, School of Medicine, Zhejiang University (IIT2018747-8). All participants provided written informed consent prior to their enrollment in this study.
