Wu, Yibo https://orcid.org/0000-0002-5431-1133
Liu, Lizhen
Chen, Yi
Lai, Xiaoyu
Chen, Yan
Lu, Ying
Yang, Luxin
Sun, Lan
He, Jiayi
Tong, Fenfang
Cao, Junjie
Li, Lin
Shi, Jimin
Zhao, Yanmin
Yuan, Xiaolin
Zhu, Panpan
Huang, He https://orcid.org/0000-0002-2723-1621
Xu, Yajing
Funding for this research was provided by:
National Natural Science Foundation of China (82170205)
National Natural Science Foundation of China (82470210)
National Natural Science Foundation of China (82300240)
Natural Science Foundation of Zhejiang Province (MS25H080015)
Article History
Received: 27 November 2025
Revised: 13 February 2026
Accepted: 12 March 2026
First Online: 24 March 2026
Competing interests
: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. YW designed the study and wrote the paper. LZL, YIC, recruiting patients, data collecting, revise paper. XL, YAC, YINL, LY, LS, JH, FT, JC, recruiting patients, data collecting. LL, JS, YZ, XLY, PZ, recruiting patients, data collecting. HH, YX, YL, funding acquisition, project administration, review and validation.