Backen, Alison C.
Lopes, Andre
Wasan, Harpreet
Palmer, Daniel H
Duggan, Marian
Cunningham, David
Anthoney, Alan
Corrie, Pippa G.
Madhusudan, Srinivasan
Maraveyas, Anthony
Ross, Paul J.
Waters, Justin S.
Steward, William P.
Rees, Charlotte
McNamara, Mairéad G.
Beare, Sandy
Bridgewater, John A. https://orcid.org/0000-0001-9186-1604
Dive, Caroline
Valle, Juan W. https://orcid.org/0000-0002-1999-0863
Article History
Received: 22 November 2017
Revised: 28 March 2018
Accepted: 3 May 2018
First Online: 21 June 2018
Competing interests
: S.B. has grants and non-financial support from AstraZeneca, outside this work. J.A.B. received personal fees from AstraZeneca during the conduct of the study. D.C. received grants from AstraZeneca, Amgen, Celgene, Merck Serono, Sanofi, Merrimack. and Medimmune, outside this work. H.W. participates in advisory boards for Lilly and AstraZeneca outside this work. J.S.W. has non-financial support from Novartis and Ipsen Pharma and personal fees from Roche outside this work. J.W.V. reports personal fees from Pfizer, grants, personal fees, and non-financial support from Novartis, personal fees from Abbott, personal fees and non-financial support from Celgene, personal fees from SIRTex, personal fees and non-financial support from Ipsen, grants, and personal fees from AstraZeneca Pharmaceuticals, outside the submitted work. D.A.A., A.C.B., P.C., C.D., M.D., A.L., S.M., A.M., M.M.N., K.M., D.H.P., C.R., P.J.R. and W.P.S. declare no competing interests.
: All authors gave final approval of the version to be published.
: Permission for this trial was granted by the North West 5 Research Ethics Committee, Haydock Park on 23 August 2010 (10/H1010/42). All patients provided written informed consent before randomisation.