Pellacani, Davide
Droop, Alastair P.
Frame, Fiona M.
Simms, Matthew S.
Mann, Vincent M.
Collins, Anne T. http://orcid.org/0000-0002-2991-2703
Eaves, Connie J.
Maitland, Norman J.
Funding for this research was provided by:
Provincial Health Services Authority, British Columbia | BC Cancer Agency (Strategic Priorities Fund, Strategic Priorities Fund)
The Freemasons’ Grand Charity
Yorkshire Cancer Research (Y257PA, Y257PA, Y257PA, Y257PA)
Article History
Received: 19 March 2018
Revised: 24 July 2018
Accepted: 27 July 2018
First Online: 15 October 2018
Competing interests
: The authors declare no competing interests.
: This work was supported by The Freemasons’ Grand Charity (D.P. and N.J.M.), Yorkshire Cancer Research program grant Y257PA (D.P., N.J.M., F.M.F., A.P.D., and A.T.C.), and British Columbia Cancer Agency (Strategic Priorities Fund, D.P. and C.J.E.).
: Prostate tissues were obtained from patients undergoing radical prostatectomy at Castle Hill Hospital (Cottingham, UK) with informed patient consent and approval from the NRES Committee Yorkshire & The Humber (LREC Number 07/H1304/121).
: All samples were obtained with informed patient consent and all data were anonymised. No individual person’s data in any recognisable form (including individual details, images or videos) are included in this manuscript. All authors agree to its submission to the British Journal of Cancer and, if accepted, to its publication in this journal.
: The methylation and coverage calls for all RRBS libraries generated are available from GEO [GSE107596]. For patients’ privacy reasons, raw data (FASTQ and BAM files) for the RRBS libraries are not publicly available, but can be available from the corresponding author on request.
: This work is published under the standard license to publish agreement. After 12 months the work will become freely available and the license terms will switch to a Creative Commons Attribution 4.0 International (CC BY 4.0).