Whitwell, Harry J.
Worthington, Jenny
Blyuss, Oleg http://orcid.org/0000-0002-0194-6389
Gentry-Maharaj, Aleksandra
Ryan, Andy
Gunu, Richard
Kalsi, Jatinderpal
Menon, Usha
Jacobs, Ian
Zaikin, Alexey
Timms, John F. http://orcid.org/0000-0002-4507-835X
Funding for this research was provided by:
Ministry of Education and Science of the Russian Federation (074-02-2018-330)
Article History
Received: 28 June 2019
Revised: 6 December 2019
Accepted: 16 December 2019
First Online: 15 January 2020
Ethics approval and consent to participate
: This nested case–control study within UKCTOCS was approved by the Joint UCL/UCLH Research Ethics Committee A (Ref. 05/Q0505/57). Written informed consent was obtained from donors and no data allowing identification of patients was provided. The study was performed in accordance with the Declaration of Helsinki.
: Not applicable.
: Raw assay data, excepting CA125, are available upon request.
: U.M. and I.J. declare financial interest through UCL Business and Abcodia Ltd in the third-party exploitation of clinical trial biobanks, which have been developed through research at UCL. The remaining authors declare no conflict of interest.
: This study, part of PROMISE, was funded through Cancer Research UK PRC Programme Grant A12677, Cancer Research UK EDC Project Award C12077/A26223 and by the Eve Appeal Gynaecological Cancer Research Trust. It was supported by the National Institute for Health Research (NIHR) University College London Hospitals (UCLH) Biomedical Research Centre. UKCTOCS was core funded by the Medical Research Council, Cancer Research UK and the Department of Health with additional support from the Eve Appeal, Special Trustees of Bart’s and the London and Special Trustees of UCLH. A.Z. acknowledges support by the grant of the Ministry of Education and Science of the Russian Federation Agreement No. 074-02-2018-330.