Updates are available Correction dated 2025-06-20

Article History

Received: 20 April 2020

Revised: 24 June 2020

Accepted: 27 July 2020

First Online: 20 August 2020

Change Date: 14 May 2025

Change Type: Update

Change Details: The original online version of this article was revised: In this article fig. 2 and 6 have been updated. U251-shCtrl, U251-shE2F7, U118-Vec and U118-E2F7 of Fig. 2e and GAPDH blot of Fig. 6b are incorrect. The soft agar images in Fig. 2e were misplaced during figure assembly. For error of Fig. 6b, the GAPDH blot was misplacd the original western blot image in the wrong file directory, which led to error in the processing and typesetting of the experimental results of subsequent manuscripts.

Change Date: 20 June 2025

Change Type: Correction

Change Details: A Correction to this paper has been published:

Change Details: https://doi.org/10.1038/s41416-025-03057-7

Ethics approval and consent to participate

: The trial protocol was compliant with good clinical practice guidelines and the Declaration of Helsinki and was approved by the ethics committee of The Second People’s Hospital of Liaocheng. All patients provided written informed consent before participation. Animal experiments were performed in compliance with the guidelines of the Institute for Laboratory Animal Research, Jining Medical University, China.

: Data and material shall be available from the corresponding authors.

: The authors declare no competing interests.

: This research was supported by the National Natural Science Foundation of China (Grants 81672502 and 81602479), the National Natural Science Foundation Cultivation Project of Jining Medical University (JYP2019KJ02) and faculty Start-up Fund for R.Y. from Jining Medical University (600788001).