Renehan, Andrew G.
Pegington, Mary https://orcid.org/0000-0002-5656-1486
Harvie, Michelle N. https://orcid.org/0000-0001-9761-3089
Sperrin, Matthew
Astley, Susan M.
Brentnall, Adam R.
Howell, Anthony
Cuzick, Jack
Gareth Evans, D.
Article History
Received: 23 August 2019
Revised: 15 January 2020
Accepted: 3 March 2020
First Online: 23 March 2020
Ethics approval and consent to participate
: The study was approved by Central Manchester Research Ethics Committee (reference: 09/H1008/81). All participants consented to partake in the study. This study was performed in accordance with the Declaration of Helsinki.
: The datasets supporting the conclusions of this article are stored in a secured research database and may be available upon presentation of formal approval.
: A.G.R. has received lecture honoraria from Merck Serona and Janssen-Cilag, and independent research funding and lecture honoraria from Novo Nordisk and Sanofi Pasteur MPS, unrelated to this study. The other authors declare no competing interests.
: This paper presents independent research funded by the National Institute for Health Research (NIHR) under its Programme Grants for Applied Research (grant reference number RP-PG-0707-10031). A.G.R., M.P., M.N.H. and D.G.E. are supported by the Manchester NIHR Biomedical Research Centre (IS-BRC-1215-20007).