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Article History

Received: 14 November 2019

Revised: 25 May 2020

Accepted: 19 June 2020

First Online: 8 July 2020

Ethics approval and consent to participate

: This study complies with TCGA policies and guidelines. Thus, no personal identifying data or images are included in this paper. This study also follows the TCGA Program that genomic sequence and variation data sets generated from the CCLE is available to researchers without requiring Data Use Certification. The study was performed in accordance with the Declaration of Helsinki. All human NSCLC, MDA-MB-231, MCF7 cell lines were purchased from ATCC. Isogenic clones of MCF-10A cells and SUM159 cell lines were acquired from our collaboration with Asst. Prof Marcin Iwanicki (Stevens Institute of Technology, NJ, USA) and Prof. Junying Yuan (Harvard Medical School, MA, USA), respectively.

: All original WB are available as Supplementary figures. All other data are available within the article and its supplementary information files.

: The authors declare no competing interests.

: This work was supported by grants from Karolinska Institutet, the Swedish Research Council (VR), Ragnar Söderberg Foundation and Swedish Cancer Society (Cancerfonden).