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Article History

Received: 12 January 2021

Revised: 22 March 2021

Accepted: 26 March 2021

First Online: 9 April 2021

Ethics approval and consent to participate

: All studies included in cited genome‐wide association studies had approved by a relevant review board and participants had given informed consent. The present MR analyses were approved by the Swedish Ethical Review Authority (2019‐02793).

: All data analyzed in this study are available in the supplemental material.

: All authors have completed the ICMJE uniform disclosure form at and declare no support from any organisation for the submitted work. The authors declare no competing interests.

: S.K. is supported by the United Kingdom Research and Innovation Future Leaders Fellowship (MR/T043202/1). A.M.M. is supported by EC‐Innovative Medicines Initiative (BigData@Heart). S.B. is supported by Sir Henry Dale Fellowship jointly funded by the Wellcome Trust and the Royal Society (204623/Z/16/Z). S.C.L. is supported by research grants from the Swedish Research Council for Health, Working Life and Welfare (Forte; grant no. 2018‐00123), the Swedish Research Council (Vetenskapsrådet; grant no. 2019–00977) and the Swedish Heart-Lung Foundation (Hjärt-Lungfonden; grant no. 20190247). Funders had no roles in the design and conduct of the study; collection, management, analysis and interpretation of the data; preparation, review or approval of the manuscript; or the decision to submit the manuscript for publication.