Funding for this research was provided by:
Cancer Research UK (C16077/A29186, C16077/A29186)
Article History
Received: 7 January 2021
Revised: 8 April 2021
Accepted: 15 April 2021
First Online: 26 May 2021
Ethics approval and consent to participate
: Ethical approval for the study was obtained from the North East Tyne and Wear South Research Ethics Committee (REC number 15/NE/0247). Individual patient consent not required as pseudonymised data used.
: Not applicable.
: The data used in this study are held by University of Oxford under a data sharing contract with Public Health England and are not available for sharing. These data are available by individual application to the Office of Data Release at Public Health England ().
: The authors declare no competing interests.
: T.G. and G.R. are funded in part by Cancer Research UK (Grant number C16077/A29186). T.G. is an employee of Oxford University Hospitals NHS Foundation Trust. I.B. received funding from Public Health England and J.B. is an employee of Public Health England.