Fotopoulou, Christina https://orcid.org/0000-0001-6375-9645
Rockall, Andrea https://orcid.org/0000-0001-8270-5597
Lu, Haonan
Lee, Philippa
Avesani, Giacomo
Russo, Luca
Petta, Federica
Ataseven, Beyhan
Waltering, Kai-Uwe
Koch, Jens Albrecht
Crum, William R.
Cunnea, Paula https://orcid.org/0000-0002-3699-4911
Heitz, Florian https://orcid.org/0000-0002-2412-0352
Harter, Philipp
Aboagye, Eric O.
du Bois, Andreas
Prader, Sonia
Article History
Received: 21 June 2021
Revised: 23 November 2021
Accepted: 1 December 2021
First Online: 18 December 2021
Competing interests
: The authors declare no competing interests for this study. CF received honoraria from Ethicon, GSK, Astra Zeneca/MSD, Tesaro, Clovis, Sequana and Roche, outside of the submitted work. BA reports personal fees and non-financial support from Roche and Tesaro/GSK; personal fees from Astra Zeneca, Clovis, Celgene, MSD and Amgen; and non-financial support from PharmaMar, outside of the submitted work. AR received travel support for an educational lecture from Guerbet Laboratories, outside of the submitted work. FH reports personal fees and non-financial support from Astra Zeneca, Roche, Tesaro, GSK and Clovis; non-financial support from NewOncology, personal fees from NovoCure and PharmaMar, outside of the submitted work. AdB reports honoraria/expenses from Roche, Astra Zeneca, GSK/Tesaro, Clove, BIOCAD, Zodiac and Amgen, and consulting/advisory board for Roche, Astra Zeneca, GSK/Tesaro, Clovis, Pfizer, BIOCAD, Genmab/Seattle Genetics, MSF and Amgen, outside of the submitted work. PH reports grants and personal fees from Astra Zeneca, Roche, Clovis, Immunogen and GSK; personal fees from Sotio, Stryker, Zai Lab, and MSD; grants from Public funding (EU, DKH and DFG); and grants from Boehringer Ingelheim, Medac, and Genmab; outside of the submitted work. The remaining authors declare no competing interests.
: Retrospective cohort study design with ethical approval for retrospective analysis of human data was obtained under the Hammersmith and Queen Charlotte’s & Chelsea Research Ethics Committee approval 05/QO406/178 and the Kliniken Essen-Mitte Research Ethics Committee approval and informed consent was waived. The study was performed in accordance with the ethical standards of the institutional and/or national research committee and with the principles of the 1964 Declaration of Helsinki and its later amendments or comparable ethical standards.
: This manuscript does not contain any individual patient data.