Seitz, Stefanie
Dreyer, Tobias F.
Stange, Christoph
Steiger, Katja http://orcid.org/0000-0002-7269-5433
Bräuer, Rosalinde
Scheutz, Leandra
Multhoff, Gabriele
Weichert, Wilko
Kiechle, Marion
Magdolen, Viktor
Bronger, Holger http://orcid.org/0000-0002-3706-6738
Funding for this research was provided by:
Deutsche Forschungsgemeinschaft (SFB1335, 360372040, SFB1335, 360372040, MA1236/10-1, BR4733/1-3, BR4733/3-1)
Article History
Received: 30 October 2021
Revised: 9 February 2022
Accepted: 15 February 2022
First Online: 21 March 2022
Competing interests
: KS receives research funding from Roche and is a member of the advisory board of TRIMT GmbH. She also has filed a patent on a radiopharmaceutical compound. WW was as a member of advisory boards and speaker for Roche, MSD, BMS, AstraZeneca, Pfizer, Merck, Lilly, Boehringer, Novartis, Takeda, Bayer, Amgen, Astellas, Eisai, Illumina, Siemens, Agilent, ADC, GSK and Molecular Health, and he reports research funding from Roche, MSD, BMS and AstraZeneca, all outside of the submitted work. MK reports renumerations von Springer Press, Biermann Press, Celgene, AstraZeneca, Myriad Genetics, TEVA, Eli Lilly, GSK, consulting for Myriad Genetics, Bavarian KVB, DKMS Life, BLAEK, TEVA, Exeltis, equity ownership in Therawis Diagnostic GmbH, AIM GmbH, funding from Sphingotec, Deutsche Krebshilfe, DFG, Senator Roesner Foundation, Dr. Pommer-Jung Foundation, Waltraut Bergmann Foundation, Bavarian State Ministry of Economy, BMBF. VM reports two other non-project-related grants from the Bavarian Ministry of Economy, Infrastructure, Transportation and Technology and from Therawis Diagnostics, respectively. HB reports grants from Deutsche Forschungsgemeinschaft (DFG), German Research Foundation during the conduct of the study, as well as personal fees from Roche, AstraZeneca, GlaxoSmithKline, Clovis, Teva, PharmaMar, and Pfizer outside the submitted work. The remaining authors declare no competing interests.
: Use of human samples was approved by the Institutional Review Board of the Technical University of Munich (Munich, Germany; approval 5747/13). Animal experiments were approved by the Government of Upper Bavaria (Regierung von Oberbayern) and were in accordance with the institutional guidelines of the Technical University of Munich. The study was performed in accordance with the Declaration of Helsinki.
: Not applicable.