Besse, Andrej
Sedlarikova, Lenka
Buechler, Lorina
Kraus, Marianne
Yang, Chieh-Hsiang
Strakova, Nicol
Soucek, Karel http://orcid.org/0000-0001-7283-8150
Navratil, Jiri
Svoboda, Marek
Welm, Alana L. http://orcid.org/0000-0002-1412-1351
Joerger, Markus
Driessen, Christoph
Besse, Lenka http://orcid.org/0000-0003-4739-7618
Funding for this research was provided by:
Krebsliga Schweiz (KFS-4990-02-2020, KFS-4990-02-2020)
European Union – Next Generation EU: National Institute for Cancer Research
U.S. Department of Health & Human Services | NIH | National Cancer Institute (U54CA224076, U54CA224076)
Agentura Pro Zdravotnický Výzkum České Republiky (NU-21-08-00023)
U.S. Department of Health & Human Services | NIH | National Cancer Institute
Research Committee of the Cantonal Hospital St. Gallen
Article History
Received: 17 July 2023
Revised: 8 June 2024
Accepted: 18 June 2024
First Online: 5 July 2024
Competing interests
: The authors declare no competing interests.
: Written informed consent was obtained from all patients, and tissue specimens, and primary cells were collected with the approval of the Masaryk Memorial Cancer Institute ethics committee (2017/1894/MOU). Samples used to derive patient-derived organoids HCI-002, HCI-010, and HCI-023 were collected with informed consent with approval of the University of Utah Institutional Review Board protocol #10924. All methods were carried out in accordance with relevant guidelines and regulations.