Cutty, SJ
Hughes, FA
Ortega-Prieto, P.
Desai, S.
Thomas, P.
Fets, LV
Secrier, M. https://orcid.org/0000-0003-2758-1741
Funding for this research was provided by:
RCUK | Medical Research Council (MC-A658-5TY60, MC-A658-5TY60, MC-A654-5QC70, MC-A654-5QC70)
Cancer Research UK (C63833/A25729, C63833/A25729, RCCCEA-Nov21\100001)
RCUK | Engineering and Physical Sciences Research Council (EP/N014529/1)
Research Councils UK (MR/T042184/1, MR/T018429/1)
RCUK | Biotechnology and Biological Sciences Research Council (BB/R01356X/1)
Wellcome Trust (204841/Z/16/Z)
Article History
Received: 3 June 2024
Revised: 12 November 2024
Accepted: 4 December 2024
First Online: 20 December 2024
Competing interests
: The authors declare no conflict of interest.
: Human samples used in this research project were obtained from the Imperial College Healthcare Tissue Bank (ICHTB). ICHTB is supported by the National Institute for Health Research (NIHR) Biomedical Research Centre based at Imperial College Healthcare NHS Trust and Imperial College London. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health. This research project was approved by a local research ethics committee, the Imperial College Healthcare Tissue Bank (ICHTB), project reference R20007. ICHTB is a Human Tissue Authority-licenced Research Tissue Bank (licence number 12275) with approval by the Health Research Authority Wales Research Ethics Committee (REC) 3 (reference 22/WA/0214) to collect and release samples for research. Samples were either sourced from participants who gave informed consent under ICHTB sub-collection reference number HIS_SD_18_025 or were obtained from the histopathology diagnostic archive of Imperial College Healthcare NHS Trust under ICHTB authority and REC approval 22/WA/0214, in accordance with the requirements of the Human Tissue Act. All methods were performed in accordance with the relevant guidelines and regulations.