Yuan, Fangcheng https://orcid.org/0000-0002-8443-6754
Jia, Guochong https://orcid.org/0000-0002-8455-1832
Wen, Wanqing https://orcid.org/0000-0002-3004-5168
Xu, Shuai https://orcid.org/0000-0002-7798-5720
Gunchick, Valerie
Deng, Kui
Long, Jirong https://orcid.org/0000-0002-7433-9766
Yu, Danxia
Shu, Xiao-Ou
Zheng, Wei https://orcid.org/0000-0003-1226-070X
Funding for this research was provided by:
Anne Potter Wilson chair endowment at Vanderbilt University
Article History
Received: 14 August 2024
Revised: 4 March 2025
Accepted: 21 March 2025
First Online: 30 April 2025
Competing interests
: The authors declare no competing interests.
: The UK Biobank study was approved by the North West Multi-Center Research Ethics Committee (approval number: 16/NW/0274) and conducted in accordance with the Declaration of Helsinki. Informed consent was obtained from all participants. The GWAS meta-analysis for CRC was approved by the South Central Ethics Committee (UK) (reference no. 17/SC/0079).