Su, Haiqi https://orcid.org/0000-0001-8014-7915
Jin, Xitong https://orcid.org/0000-0002-8561-046X
Kong, Linghua https://orcid.org/0000-0002-0270-0540
You, Yan https://orcid.org/0000-0003-4971-7830
Wu, Huanwen https://orcid.org/0000-0002-3996-3176
Liou, Yuligh https://orcid.org/0000-0003-3994-6250
Article History
Received: 19 September 2024
Revised: 3 March 2025
Accepted: 26 March 2025
First Online: 10 April 2025
Competing interests
: The authors declare no competing interests.
: The Institutional Review Board of Peking Union Medical College Hospital has approved this study (No. JS-2380 and K-S2021211 for METHY3 and METHY4 respectively). The registration numbers are NCT04646954 and NCT05290428 (clinicaltrials.gov, registered on November 26, 2020 and March 12, 2022), respectively. Informed consent was obtained from the subjects prior to participating in the study. All methods were performed in accordance with the relevant guidelines and regulations.
: Consent for publication has been obtained from all patients.