Lee, Hyun Jin
Lee, Jun Hyeong
Kang, Junho
Kim, Kyeonghui
Cho, Youngwon
Park, Jihyun
Song, Sang-Hyun
Kwon, Joonha
Kim, Young-Joon
Park, Woong-Yang
Kim, Tae-You
Park, Jong-Eun
Kim, Pilnam https://orcid.org/0000-0002-5592-4599
Choi, Jung Kyoon
Article History
Received: 28 March 2025
Revised: 22 July 2025
Accepted: 28 August 2025
First Online: 15 September 2025
Competing interests
: The authors declare no competing interests.
: Human tissue collection and pdECM matrix preparation was approved by the Institutional Review Board at Korea Advanced Institute of Science and Technology (KAIST), Republic of Korea (approval no.: KH2018-54), and the Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea (approval no.: 4-2012-0859). Culture of CRC organoid was approved by the Institutional Review Board of Seoul National University Hospital (approval number: 1608-054-784, 1710-102-896). The study was conducted in accordance with the relevant guidelines and regulations. All participants provided written informed consent for sample collection; the study was performed in accordance with the Declaration of Helsinki.