Lutz, Manfred P. https://orcid.org/0000-0003-1989-4553
Ansorge, Nikolaus
Barmashenko, Gleb
Bauer, Hans
Burkart, Christof
Decker, Thomas
Ettrich, Thomas https://orcid.org/0000-0002-7654-2442
Fischer von Weikersthal, Ludwig
Geer, Thomas
Gerhardt, Anke
Höfling, Sabine
Jacobasch, Lutz
Koenigsmann, Michael
Leidig, Tobias
Plentz, Ruben
Räth, Sebastian
Reichert, Dietmar
Schulte, Markos
Schulte, Nadine
Schwarzer, Andreas
Siegler, Gabriele
Waldschmidt, Dirk
Karthaus, Meinolf
Funding for this research was provided by:
Servier Deutschland GmbH
Article History
Received: 24 March 2025
Revised: 30 July 2025
Accepted: 1 September 2025
First Online: 14 October 2025
Competing interests
: ML: Financial Interests, Personal, Research Funding: Servier. CB: Financial Interests, Personal, Advisory Board: Boehringer Ingelheim, Amgen, Bayer. TD: Financial Interests, Personal, Advisory Board: Novartis, Iomedico; Financial Interests, Personal, Invited Speaker: Novartis, Lilly. AG: Financial Interests, Personal, Royalties: Janssen; Financial Interests, Personal, Advisory Board: Janssen, Incyte, Novartis, Shire. MK: Financial Interests, Personal, Advisory Board: AbbVie, AstraZeneca, Bristol Myers Squibb, Celgene, Janssen, Gilead, Novartis, Pfizer, Roche; Financial Interests, Advisory Board: Takeda. JS: Stock Ownership in Biontech SE. GS: Financial Interests, Personal, Advisory Board: BMS, Novartis, Roche, MSD, Janssen; Financial Interests, Personal, Invited Speaker: Janssen; Financial Interests, Institutional, Local PI: BMS, MSD, AstraZeneca; Non-Financial Interests, Principal Investigator: BMS, MSD, AIO GmbH, IKFZ, AstraZeneca, GLA; Non-Financial Interests, Member: AIO, DGHO, EORTC, DKG. DW: Financial Interests, Personal, Other, Travel: AstraZeneca, Bristol Myers Squibb, Eisai, Roche; Financial Interests, Personal, Speaker’s Bureau: AstraZeneca, Bayer, Bristol Myers Squibb, Eisai, Falk, Incyte. All remaining authors have declared no conflicts of interest.
: The study was performed in accordance with the Declaration of Helsinki. An independent ethics committee (Ethics Committee of the Medical Association of Saarland) reviewed the study and any amendments. Written informed consent was obtained from each patient before any study specific medical procedure was performed.