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Profilin-2 promotes tumour aggressiveness in oral squamous cell carcinoma via HDAC1 modulation: implications for EMT and targeted therapy

Published Online: 2025-11-07

Published Print: 2026-01-31

Authors

Lin, Li-Han

Chang, Kuo-Wei

Cheng, Hui-Wen

Liu, Chung-Ji https://orcid.org/0000-0002-0385-869X
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Text and Data Mining valid from 2025-11-07

Version of Record valid from 2025-11-07
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Article History

Received: 1 February 2025

Revised: 12 August 2025

Accepted: 5 September 2025

First Online: 7 November 2025

Competing interests

: The authors declare no competing interests.

: This study was approved by the Institutional Review Board of MacKay Memorial Hospital (approval number: 20MMHIS437e), and written informed consent was obtained from all participants. All procedures were performed in accordance with the relevant guidelines and regulations. Animal experiments were approved by the Institutional Animal Care and Use Committee of MacKay Memorial Hospital (approval number: MMH-A-S-107-70) and conducted in compliance with institutional and international standards for the care and use of laboratory animals.

: All authors have approved the manuscript and agree with its submission to Cancer Science.

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